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Intravenous levetiracetam for treatment of neonatal seizures

Journal title
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Publication year
2013
Author(s)
Rakshasbhuvankar, A.; Rao, S.; Kohan, R.; Simmer, K.; Nagarajan, L.
Pages
1165-7
Volume
20
Number
8

In this case series we report on eight neonates with refractory seizures who received intravenous levetiracetam when seizures did not respond to two or more conventional anticonvulsants. Six of the eight neonates had an excellent response with either cessation, or reduction in seizures by at least 80%. One neonate showed a partial response while one did not have any reduction in seizure frequency. We did not encounter any adverse effects that could be attributable to levetiracetam.

Research abstracts