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The Effect of Noncardiac and Genetic Abnormalities on Outcomes Following Neonatal Congenital Heart Surgery

Journal title
Seminars in thoracic and cardiovascular surgery
Publication year
2016
Author(s)
Alsoufi, B.; Gillespie, S.; Mahle, W. T.; Deshpande, S.; Kogon, B.; Maher, K.; Kanter, K.
Pages
105-14
Volume
28
Number
1

Significant noncardiac and genetic abnormalities (NC and GA) are common in neonates with congenital heart defects. We sought to examine current-era effect of those abnormalities on early and late outcomes following cardiac surgery. The method from 2002-2012, 1538 neonates underwent repair (n = 860, 56%) or palliation (n = 678, 44%) of congenital heart defects. Regression models examined the effect of NC and GA on operative results, resource utilization, and late outcomes. Neonates with NC and GA (n = 312, 20%) had higher incidence of prematurity (21% vs 13%; P < 0.001) and weight

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